Drug-induced liver injury is a major cause of paediatric liver disease including cholestasis, accounting for almost 20% of cases of acute liver failure in children, and is a major reason for liver transplantation.45
45. Amin MD, Harpavat S, Leung DH. Drug-induced liver injury in children. Curr Opin Pediatr 2015;27:625-33.
46. Van Eyken P, Nemolato S, Faa G, Ambu R. Hepatic injury to the newborn liver due to drugs. Curr Pharm Des 2012;18:3050-60.